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I had been working on several statistical problems involving Gaussian processes.  On my first pass, I could barely understand anything in this book.  After returning to it several times, more and more of it started clicking and I started gaining much deeper insights into the problems I was facing.  I also became awestruck by the sheer scope and generality of this book as it is nearly a complete accounting of what we know about Gaussian processes even in very abstract spaces.  To this day, I feel like I learn something new every time I look through it.