Evan Pugh (1859-1864)
William Henry Allen (1864-1866)
John Fraser (1866-1868)
Thomas Henry Burrowes (1868-1871)
James Calder(1871-1880)
Joseph Shortlidge (1880-1881)
The James Y. McKee Interregnum (1881-1882)
George W. Atherton (1882-1906)
The James A. Beaver Interregnum (1906-1908)
Edwin Erle Sparks (1908-1920)
John Martin Thomas (1921-1925)
Ralph Dorn Hetzel (1927-1947)
The James Milholland Interregnum (1947-1950)
Milton Stover Eisenhower (1950-1956)
Eric A. Walker (1956-1970)
John W. Oswald (1970-1983)
Bryce Jordan (1983-1990)
Joab Thomas (1990-1995)
Graham Spanier (1995-2011)
Rodney Erickson (2011- 2014)
Eric J. Barron (2014- 2022)
Neeli Bendapudi (2022- present)